Ducati Multistrada V4 / V4S (2021) Review: The Ultimate Adventure Touring Machine
Ducati has long been a dominant force in the adventure touring segment, and with the Multistrada V4 and V4S (2021), the brand pushes the envelope even further. Known for blending superbike-level performance with long-distance touring capability, the Multistrada V4 series brings an all-new V4 engine, cutting-edge rider aids, and unmatched comfort. But does it live up to the hype? Let’s take a deep dive into what makes this bike stand out and who it’s best suited for.
Design & Aesthetics
At first glance, the Ducati Multistrada V4 is unmistakably a Ducati—aggressive yet refined. It retains the signature beak-style front end, sharp LED lighting, and muscular bodywork that give it an unmistakable presence. The aluminum monocoque frame ensures strength without excessive weight, while the aerodynamic design enhances high-speed stability.
Ducati Multistrada V4 / V4S (2021) Accessories & Parts Collection
Available in Ducati Red and Aviator Grey, the bike exudes a premium feel. The V4S variant also offers a semi-active electronic suspension and adaptive cruise control, adding both performance and practicality.
Engine & Performance
The heart of the Multistrada V4 is its all-new 1,158cc V4 Granturismo engine, producing an impressive 170 hp @ 10,500 rpm and 125 Nm of torque @ 8,750 rpm. Unlike the previous Desmodromic engines, this new unit utilizes conventional valve springs, reducing maintenance intervals to 37,000 miles—a significant advantage for long-distance riders.

Riding Experience
Whether carving through twisties, cruising on highways, or tackling off-road terrain, the Multistrada V4 is an absolute powerhouse. The acceleration is effortless, and the top speed easily exceeds 150 mph. Thanks to the lightweight V4 engine, handling feels nimble, and the 6-speed gearbox with a quick shifter ensures seamless gear transitions.
Ideal Use Case
The Multistrada V4S is built for serious touring enthusiasts, yet it retains enough agility for urban riding. With Ducati Skyhook Suspension (DSS) and various riding modes, it adapts effortlessly to different terrains—whether it’s long highway cruises or off-road adventures.
Technology & Features
Ducati left no stone unturned when it comes to technology. The 6.5-inch TFT display features Ducati Connect, allowing riders to integrate smartphones for navigation, calls, and music. Advanced rider aids include:
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Cornering ABS
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Wheelie control
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Traction control
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Adaptive cruise control (exclusive to the V4S)
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Blind-spot detection
The introduction of radar-assisted safety features makes the Multistrada V4 one of the safest adventure bikes on the market.
Comfort & Ergonomics
Ducati has significantly improved rider comfort, with an adjustable 840mm-860mm seat height, a wider, more cushioned saddle, and redesigned handlebars for better reach. The winglets on the fairing help direct heat away from the rider, ensuring a comfortable experience even on long-haul rides.

The semi-active suspension (V4S model) adapts in real-time to road conditions, making potholes and rough surfaces barely noticeable. Pillion comfort is also a priority, with larger grab handles and improved seat cushioning.
Braking & Safety
Equipped with Brembo Stylema calipers and 320mm twin discs, the Multistrada V4 offers exceptional stopping power. The inclusion of Cornering ABS ensures safety even in aggressive braking scenarios.
Fuel Efficiency & Maintenance
Despite its power, the Multistrada V4 is surprisingly fuel-efficient, averaging 40 mpg under mixed riding conditions. With a 22-liter fuel tank, riders can expect a range of approximately 200+ miles on a full tank—perfect for long-distance touring.
The switch from Ducati’s traditional Desmodromic valves to standard valve springs means the major valve service is only required every 37,000 miles, significantly reducing maintenance costs.
Comparison & Competitors
The Ducati Multistrada V4S goes head-to-head with top adventure bikes like the BMW R 1250 GS and the KTM 1290 Super Adventure S. Here’s how it stacks up:
Feature | Ducati Multistrada V4S | BMW R 1250 GS | KTM 1290 Super Adventure S |
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Engine | 1,158cc V4 | 1,254cc Boxer Twin | 1,301cc V-Twin |
Power | 170 hp | 136 hp | 160 hp |
Torque | 125 Nm | 143 Nm | 138 Nm |
Weight | 240 kg | 249 kg | 220 kg |
Suspension | Semi-active DSS | Dynamic ESA | WP Semi-active |
Radar Tech | Yes | No | No |
The Multistrada V4S outshines its rivals in terms of power, technology, and maintenance intervals, making it a compelling choice for riders looking for a high-tech, high-performance tourer.
Ducati Supersport 950 / 950S (2021) Performance Parts & Upgrades
Ideal Riders & Target Audience
Who should consider the Ducati Multistrada V4S?
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Long-distance tourers who demand power, comfort, and tech.
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Adventure seekers looking for an off-road-capable machine.
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Tech-savvy riders who appreciate radar-assisted safety features.
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Performance enthusiasts wanting sportbike-like speed in a tourer.
Conclusion & Final Verdict
The Ducati Multistrada V4 / V4S (2021) is a game-changer in the adventure touring world. With exceptional power, cutting-edge technology, improved comfort, and reduced maintenance needs, it’s a motorcycle built for the modern adventurer.
While the price tag is premium, the features, performance, and innovation justify the investment. If you’re looking for an adventure bike that combines Ducati’s racing DNA with long-distance comfort, the Multistrada V4S is hard to beat.